Human 2',5'-Oligoadenylate Synthetase 3 (OAS3) ELISA Kit

OAS3 is an interferon-induced enzyme that catalyzes the formation of 2',5'-linked oligoadenylates, key effectors in the innate antiviral response that activate RNase L to degrade viral RNA. Researchers studying type I interferon signaling, viral restriction pathways, or inflammatory cytokine cascades rely on quantitative measurement of OAS3 protein levels in human specimens.

The Assay Genie ELISA Kit provides an immunoassay for human OAS3, packaged in a 96 assays format with reagents sufficient for a full microplate run. The assay uses human-reactive antibodies validated for measurement in serum, tissue homogenates, and related sample matrices. Applications include investigation of the OAS/RNase L pathway in viral infection models, autoimmune disease research where interferon signatures are dysregulated, and biomarker discovery in inflammatory conditions.

Each kit includes a pre-coated plate, calibration standards, and detection reagents, with colorimetric readout compatible with standard microplate readers. Reagents should be stored according to the enclosed insert to maintain activity; refrigeration is recommended, and the assay is intended for research use only, supporting reproducible quantification of this key innate immunity enzyme across experimental replicates.