Human 2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP) ELISA Kit

Assay Genie offers an ELISA Kit for the quantitative detection of human 2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP) in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids. The kit is intended for research use only within the neurosciences, where CNP — an enzyme primarily found in the brain and the third most abundant protein in central nervous system myelin — has been linked to neurological disorders such as multiple sclerosis and Alzheimer's disease, giving researchers a tool to study CNP levels across disease states.

Manufacturer performance figures include a detection range of 0.312-20ng/mL, a sensitivity of 0.15ng/mL, an intra-assay CV of 4.2% and an inter-assay CV of 7.9%. Reported linearity spans 92-119% across serum, EDTA plasma and heparin plasma dilutions, with recovery ranges of 89-101% for serum and 91-103% for plasma. The assay recognises natural and recombinant human CNP, which exists as monomers and homodimers.