Guinea pig Endothelin 1 (EDN1) ELISA Kit

Endothelin-1 (EDN1) is a 21-amino acid vasoactive peptide secreted primarily by vascular endothelial cells, with potent vasoconstrictor activity mediated through ETA and ETB receptors. The Assay Genie guinea pig Endothelin-1 competitive ELISA kit provides quantitative measurement of this peptide using a competitive immunoassay format suited to small-molecule peptide analytes, with a colorimetric readout at the end of each run.

Researchers studying hypertension, atherosclerosis, pulmonary vascular remodeling, and cardiac remodeling in guinea pig models can run up to 96 assays per kit, with sample compatibility extending across tissue homogenates, cell lysates, cell culture supernatants, and standard liquid biospecimens. This flexibility accommodates both in vivo tissue sampling and in vitro cell-based experiments within a single standardized protocol.

The competitive assay format is chosen because EDN1's 21-residue length offers limited epitopes for matched-antibody capture immunoassays. Antibody specificity is directed to the guinea pig EDN1 isoform, and the assay has been validated exclusively for that species. Each kit includes pre-coated microplate strips and reagents sufficient for the complete 96-assay run.