ETS1 Transcription Factor Activity Assay

ETS1 is a member of the ETS family of transcription factors that recognizes the GGAA/T consensus DNA motif and governs genes controlling immune cell differentiation, angiogenesis, and lymphoid development. This DNA-Binding ELISA Kit from Assay Genie is formatted as a 96 Assays plate pre-coated with an ETS1-specific oligonucleotide, letting researchers quantify transcription factor binding activity in nuclear and cell lysates with a colorimetric readout. Validated reactivity across human, mouse, and rat nuclear extracts supports comparative studies in immunology, oncology, and vascular biology, where ETS1 activity in T cells, NK cells, and tumor tissue is frequently interrogated. For sample handling, prepare nuclear extracts from fresh or frozen cell pellets, aliquot lysates, and limit freeze-thaw cycles to preserve DNA-binding activity.