CDX2 Transcription Factor Activity Assay

CDX2 (Caudal Type Homeobox 2) is an intestine-specific transcription factor that governs intestinal epithelial differentiation and lineage specification. This DNA-binding activity assay from Assay Genie measures the functional DNA-binding capacity of activated CDX2 in nuclear and cell lysates, supporting research into colorectal carcinoma, Barrett's esophagus, and gastric intestinal metaplasia. The microplate-based workflow accommodates up to 96 Assays and is validated for human, mouse, and rat samples, making it useful for translational studies comparing CDX2 activity across model systems and patient-derived tissues. Store reagents according to the supplied protocol and avoid repeated freeze-thaw cycles of the nuclear extract to preserve binding activity. For research use only; not intended for diagnostic applications.