Canine Matrix Metalloproteinase 3 (MMP3) ELISA Kit

MMP3, also known as Stromelysin-1, is a zinc-dependent endopeptidase that degrades extracellular matrix components including collagen types III, IV, IX, and X, proteoglycans, fibronectin, and laminin. This colorimetric immunoassay from Assay Genie provides quantitative measurement of canine MMP3 concentrations. The kit supports research into osteoarthritis progression, cranial cruciate ligament rupture, cartilage degradation, and synovial inflammation in dogs, where elevated MMP3 levels serve as a key biomarker of active joint remodeling.

Intended for research use only, the assay accepts canine serum samples, plasma samples, and prepared tissue homogenates, with all reagents supplied in ready-to-use vials sufficient for 96 determinations. The protocol follows a standard microplate workflow with straightforward incubation and wash steps, producing a measurable signal proportional to MMP3 abundance. Results generated with this kit have been used to investigate post-operative recovery, response to disease-modifying treatments, and breed-specific susceptibility to degenerative joint conditions in veterinary research settings.