Bovine Osteopontin (SPP1) ELISA Kit

This Sandwich ELISA kit from Assay Genie is designed for the quantitative measurement of osteopontin (SPP1) in bovine samples, using an ELISA detection method. The kit is reactive with bovine species.

According to the manufacturer, the assay has a detection range of 0.312-20ng/mL and a sensitivity of 0.083ng/mL. It is validated for serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, and shows specificity for natural and recombinant bovine osteopontin. Synonyms for the target include Bone sialoprotein 1, Secreted phosphoprotein 1, SPP-1, and OPN.

Osteopontin (SPP1) is described in the source as a secreted protein involved in processes such as bone remodeling, immune response, and cell adhesion. The protein functions as a cytokine that enhances production of interferon-gamma and interleukin-12 while reducing production of interleukin-10, and is essential in the pathway leading to type I immunity. It binds tightly to hydroxyapatite and appears to form an integral part of the mineralized matrix. The UniProt accession is P31096, and the highlighted research area is cancer. The product is intended for research use only.