Bovine Ferritin heavy chain (FTH1) ELISA Kit

From Assay Genie, this Sandwich ELISA Kit is designed for the accurate measurement of bovine ferritin heavy chain (FTH1) levels in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. The assay recognises natural and recombinant bovine ferritin heavy chain with high specificity, providing a reliable tool for research into iron metabolism and conditions linked to ferritin dysregulation, including iron overload, anemia and neurodegenerative disorders.

Quantitative performance figures quoted by the manufacturer include a detection range of 1.56-100 ng/ml and a sensitivity of 0.58 ng/ml. The kit is supplied for research use only and falls within the Neurosciences research area.

Ferritin heavy chain stores iron in a soluble, non-toxic, readily available form and is important for iron homeostasis. It has ferroxidase activity, taking up iron in the ferrous form and depositing it as ferric hydroxides after oxidation, and plays a role in the delivery of iron to cells, including iron uptake in capsule cells of the developing kidney. The target protein is catalogued under UniProt entry O46414 (FRIH_BOVIN), with NCBI official symbol FTH1 and a molecular weight of 21,052 Da.