Bovine C-C motif chemokine 20 (CCL20) ELISA Kit

Manufactured by Assay Genie, this Sandwich ELISA Kit is designed for the quantitative measurement of Bovine C-C motif chemokine 20 (CCL20) using a colorimetric detection method. The kit is reactive with bovine samples and is intended for research use only within the field of immunology. Listed synonyms for CCL20 include Macrophage inflammatory protein 3 alpha, Small-inducible cytokine A20, MIP-3-alpha, MIP3A, and SCYA20.

According to the manufacturer, the assay has a detection range of 15.6-1000pg/mL and a sensitivity of 7.8pg/mL. The target protein has a stated molecular weight of 10,964 Da and is localised to the secreted subcellular compartment. The associated UniProt accession is Q8SQB1 and the NCBI Gene ID is 281666.

The kit is suitable for use with serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids, with stated specificity for natural and recombinant bovine C-C motif chemokine 20. The manufacturer describes CCL20 as a ligand for C-C chemokine receptor CCR6 that mediates chemotaxis of dendritic cells, effector/memory T-cells and B-cells, and plays roles at skin and mucosal surfaces under homeostatic and inflammatory conditions, as well as in cancer and autoimmune disease pathology.