Anti-Rituximab (Rituxan®, Mabthera®)ADA Qualitative ELISA Kit

The Anti-Rituximab ADA Qualitative ELISA Kit from Assay Genie is a bridging-format immunoassay that qualitatively screens patient specimens for antibodies directed against the chimeric anti-CD20 monoclonal antibody rituximab. The assay detects both IgG and IgM isotypes against Rituxan and Mabthera, supporting pharmacokinetic studies, biosimilar comparability work, and immunogenicity monitoring in patients on long-term therapy. A 10 µL sample volume per well is required, and the protocol fits standard laboratory workflows. The kit uses break-apart well strips in a 96 Assays configuration, allowing laboratories to conserve reagents when running partial plates. Researchers apply this kit to evaluate anti-drug antibody responses that may affect drug clearance, efficacy, or safety profiles in clinical and pre-clinical studies.