Pyrintegrin, 1 mg

A small-molecule research reagent from STEMCELL Technologies that promotes the activation of β1 integrin and supports the survival of human pluripotent stem cells in culture. The compound also acts as a RHO/ROCK pathway inhibitor, blocking the activity of ROCK1 and ROCK2, and functions as a non-muscle myosin II (NM II) ATPase inhibitor. It is intended for laboratory research use, with handling and storage guidance provided in the Product Information Sheet.

Supplied as a crystalline solid with a molecular weight of 451.5 and the molecular formula C23H25N5O3S (CAS 1228445-38-2). Reported solubility values are ~0.1 mg/mL in a 1:1 solution of DMF:PBS (pH 7.2), ~1 mg/mL in EtOH, ~30 mg/mL in DMSO, and ~50 mg/mL in DMF. The substance is not classified as hazardous under the 2012 OSHA Hazard Communication Standard (29 CFR 1910.1200) and is stable under recommended transport and storage conditions; it is incompatible with strong oxidizing agents.