NeuroCult SM1 Without Antioxidants

Formulated for the in vitro expansion of neural stem and progenitor cells, this serum-free additive from STEMCELL Technologies supplies the antioxidant-free version of NeuroCult SM1. Removing the antioxidant component gives researchers direct control over oxidative conditions in culture, supporting studies of reactive oxygen species signaling, neurodegeneration models, and redox-sensitive lineage decisions. The supplement combines with NeuroCult Basal Medium to maintain proliferation of cells as free-floating neurospheres or adherent monolayers. Supplied as a 10 mL vial sufficient for preparing 100 mL of complete proliferation medium, the product is stored frozen at -20 °C and thawed immediately before use; aliquots remain stable for several weeks when refrigerated. Researchers commonly pair this reagent with recombinant EGF and bFGF for sustained passage of embryonic or adult CNS-derived neural precursors, and each lot is qualified using clonal sphere-forming assays to confirm reproducible expansion across passages. The format supports cell culture workflows and is intended for research use only.