NeuroCult SM1 Neuronal Supplement

A serum-free supplement from STEMCELL Technologies, developed for the culture of primary tissue-derived neurons and human pluripotent stem cell (hPSC)-derived neural progenitor cells. The formulation, known as NeuroCult SM1 (STEMCELL Modified-1), was developed based on the published formulation of Brewer's B27 supplement (Brewer et al.).

It has been optimized to reproducibly support increased survival and maturation of functional neurons in both short- and long-term cultures, with minimal glial cell contamination (< 1% GFAP+). The supplement may be used in combination with BrainPhys Neuronal Medium, or as a serum-replacement supplement for customizable applications. It is also a component of BrainPhys Neuronal Medium and SM1 Kit, BrainPhys Neuronal Medium N2-A & SM1 Kit, and BrainPhys Primary Neuron Kit.