Cytomegalovirus (CMV) Antigen Slides

Provided as a ready-to-use substrate for indirect immunofluorescence assays (IFA), this Cytomegalovirus (CMV) antigen slide set from Antibodies.com enables detection of virus-specific IgG and IgM antibodies in clinical serum samples. Each set contains five individually packaged eight-well slides, with each well presenting acetone-fixed human fibroblasts infected with Human Cytomegalovirus, so viral immediate-early and late antigens are displayed across the cell monolayer for antibody binding.

The slides support qualitative serology workups relevant to diagnosing primary CMV infection, reactivation, or past exposure in transplant recipients, pregnant women, and immunocompromised patients. The eight-well configuration allows several patient specimens, positive and negative controls, or serial dilutions to be processed in parallel on a single slide, conserving sample volume. Each slide is for single use to prevent cross-contamination between specimens.

During IFA staining, patient serum antibodies bind to CMV antigens expressed in infected fibroblasts and are visualized on a fluorescence microscope via a fluorescein isothiocyanate (FITC)-conjugated secondary antibody, producing a characteristic nuclear or cytoplasmic fluorescence pattern. The product is supplied as one set of five slides and is for research use only, intended for laboratory professionals performing CMV serology.