Zebularine, 10 mg

STEMCELL Technologies supplies this laboratory research compound for research use only. The substance is a crystalline solid, also known by the synonym NSC 309132, with the systematic name 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one. Its molecular formula is C9H12N2O5 and molecular weight is 228.2, with CAS number 3690-10-6.

According to the manufacturer's Safety Data Sheets, the compound is not classified as a hazardous substance or mixture under GHS criteria and is not WHMIS controlled. It is chemically stable under normal conditions, though incompatible with strong oxidizing agents. Hazardous decomposition products include carbon dioxide, carbon monoxide, and nitrogen oxides. Reported solubility values are approximately 10 mg/mL in PBS (pH 7.2), 0.25 mg/mL in EtOH, 14 mg/mL in DMSO, and 5 mg/mL in DMF.

Published toxicological data for the compound in mice include an intraperitoneal TDLO of 9 g/kg/18D (intermittent), an oral TDLO of 9 g/kg/18D (intermittent), and an intraperitoneal TDLO of 7000 mg/kg/7D (intermittent). No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen by IARC, NTP, or OSHA. The product is for research use only and is not intended for human or animal diagnostic or therapeutic uses. The manufacturer's emergency contact number is 1-800-667-0322.