Valproic Acid (Na Salt), 10 g

Valproic acid sodium salt is a small-molecule epigenetic modulator widely used in biomedical research. The compound acts as a broad-spectrum histone deacetylase (HDAC) inhibitor, altering chromatin accessibility and gene expression patterns in cultured cells. In stem cell workflows, it is routinely included in reprogramming cocktails to boost the efficiency of induced pluripotent stem cell (iPSC) generation from somatic fibroblasts and other primary cell types. Researchers also employ valproic acid sodium salt in neural differentiation protocols, cardiomyocyte induction, cancer cell line studies, and investigations of seizure-related mechanisms in vitro.

This 10 g unit is supplied as a lyophilized or crystalline powder in a single-use bottle and is soluble in aqueous buffers, making it straightforward to prepare stock solutions for cell culture applications. Working concentrations typically range from 0.5 to 2 mM, depending on cell type and exposure duration. For best results, store the powder at room temperature, protected from light and moisture, and aliquot reconstituted stocks for short-term refrigerated use; avoid repeated freeze-thaw cycles of working solutions. The product is intended for research use only and supports in vitro studies, including chromatin immunoprecipitation, western blot analysis of acetylation marks, and flow cytometry-based assessments of histone acetylation status. Each lot is quality controlled by STEMCELL Technologies to deliver reproducible performance across pluripotent stem cell maintenance and directed differentiation experiments.