Trichostatin A, 5 mg

STEMCELL Technologies supplies Trichostatin A (TSA), a potent inhibitor of histone deacetylase (HDAC) that prevents the removal of acetyl groups from lysine residues on histone tails. The compound carries CAS number 58880-19-6, has the molecular formula C17H22N2O3, and a molecular weight of 302.4.

As a broad-spectrum HDAC inhibitor and antifungal antibiotic, Trichostatin A promotes histone hyperacetylation, which modulates chromatin structure and gene transcription. Its HDAC inhibition leads to cell cycle arrest, cell differentiation, and apoptosis across various mammalian cell types and cancer cell lines. The product is also classified as an epigenetic modifier that inhibits histone deacetylase, including HDAC1, supporting research workflows in epigenetics.

Solubility data indicate the compound is soluble in DMSO and insoluble in water and ethanol, with a recommended stock concentration of 10 mM in fresh, anhydrous DMSO.