STAT5 Inhibitor, 5 mg

Targeting the JAK-STAT signaling pathway, this STAT5 Inhibitor from STEMCELL Technologies is supplied as 5 mg of lyophilized powder in a single-use vial for in vitro research use. Investigators apply the compound in cell culture to block STAT5 phosphorylation and dissect cytokine-driven transcriptional responses downstream of IL-3, IL-5, GM-CSF, and erythropoietin receptors. The inhibitor is widely used in studies of hematopoietic stem and progenitor cell biology, where STAT5 activity governs self-renewal and survival decisions. In oncology research, blocking STAT5 with this reagent enables mechanistic studies of leukemia and lymphoma cell lines dependent on constitutive pathway activation. Recommended working concentrations typically fall in the low micromolar range, with stock solutions prepared in DMSO and stored frozen, protected from light, with limited freeze-thaw cycles to preserve compound integrity.