SCR7, 5mg

A selective small-molecule inhibitor of DNA ligase IV, SCR7 suppresses the non-homologous end joining (NHEJ) pathway and shifts double-strand break repair toward homology-directed repair (HDR), making it a useful adjunct in CRISPR-Cas9 genome editing workflows. The compound is supplied by STEMCELL Technologies as a 5 mg vial of lyophilized powder intended for in vitro and cell culture applications, where it is typically reconstituted in DMSO and added to culture medium at working concentrations in the low micromolar range to boost knock-in efficiency in mammalian cells and model embryos. For research use only; not intended for diagnostic or therapeutic procedures. Store desiccated at room temperature and protect from light to preserve activity.