Rapamycin, 10 mg

A research-grade mTOR pathway inhibitor supplied as a 10 mg lyophilized powder in a sealed vial for cell culture and stem cell differentiation workflows. This macrolide compound, originally isolated from Streptomyces hygroscopicus, is widely used to suppress mechanistic target of rapamycin (mTOR) signaling, enabling controlled modulation of cell growth, autophagy, and immune responses in vitro.

STEMCELL Technologies provides this reagent for research use only, with recommended storage at -20 °C protected from light to preserve potency over extended experimental timelines. Researchers commonly dissolve the contents in DMSO or ethanol to prepare concentrated stock solutions, then dilute into culture medium at working concentrations typically in the low nanomolar range.

Applications include maintaining naïve pluripotency in human and mouse embryonic stem cells, inducing differentiation into specific lineages, and probing autophagy in cancer and immunology studies. Each 10 mg vial supports numerous experiments depending on dosing requirements, offering a practical format for laboratories conducting long-term cell-based assays and signal transduction research.