PluriSIn-1, 10 mg

A selective small-molecule stearoyl-CoA desaturase 1 (SCD1) inhibitor supplied as 10 mg of lyophilized powder in a single vial, PluriSIn-1 is widely used in stem cell biology to selectively eliminate residual undifferentiated human pluripotent stem cells from differentiated cultures. Working concentrations in cell culture typically fall in the low micromolar range, where the compound induces ER stress and apoptosis specifically in hPSCs while sparing differentiated progeny. The molecule is soluble in DMSO and is intended for research use only. Store the powder at -20 degrees C, protected from light and moisture, and aliquot reconstituted stocks to minimize freeze-thaw cycles. Each vial from STEMCELL Technologies provides sufficient material for multiple standard differentiation-purification experiments.