NU7441, 10mg

A small-molecule research reagent supplied by STEMCELL Technologies, identified by the synonym KU57788 and CAS number 503468-95-9. The compound acts as an inhibitor of DNA-dependent protein kinase (DNA-PK), an enzyme involved in the non-homologous end joining (NHEJ) DNA repair pathway.

The product presents as a solid with a crystalline appearance. Reported molecular weight is 413.5 and molecular formula is C25H19NO3S. Reported solubility values are ~0.2 mg/mL in a 1:4 solution of DMF:PBS (pH 7.2); ~0.1 mg/mL in DMSO; ~1 mg/mL in DMF. The chemical is not classified as hazardous according to the 2012 OSHA Hazard Communication Standard or the Globally Harmonized System (GHS). It is stable under normal conditions, incompatible with strong oxidizing agents, and hazardous decomposition products include carbon dioxide, carbon monoxide, hydrogen sulfide, and nitrogen oxides (NOx).

Products are for research use only and not intended for human or animal diagnostic or therapeutic uses unless otherwise stated.