L755507, 5 mg

STEMCELL Technologies supplies this small molecule as a potent and selective β3 adrenergic receptor agonist that demonstrates >440-fold selectivity over β1 and β2 binding. The compound is a crystalline solid with a molecular weight of 584.7 g/mol and a purity of ≥98%.

Published research applications cover differentiation, gene editing, and metabolism. The compound has been reported to stimulate lipolysis in human white adipose tissue, to improve the efficiency of homology-directed repair in human induced pluripotent stem cells following CRISPR editing, and to increase metabolism in rhesus monkeys.

According to the manufacturer, the product is stable for 12 months from the date of receipt when stored as supplied, and should be protected from prolonged exposure to light. The compound is soluble in DMSO at concentrations up to 40 mM and in absolute ethanol up to 30 mM, but exhibits low solubility in aqueous media.