IWP-2, 10 mg

This small molecule from STEMCELL Technologies is a WNT pathway inhibitor that acts at the level of the pathway activator Porcupine. It is also known by the synonym Inhibitor of WNT Production-2. The product is supplied as a crystalline solid, with the chemical name N-(6-methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide (CAS No. 686770-61-6) and a molecular formula of C22H18N4O2S3, corresponding to a molecular weight of 466.6. The compound is intended for research use only and is not for human or animal diagnostic or therapeutic uses unless otherwise stated; it is manufactured under a quality management system certified to ISO 13485.

Solubility data indicate approximately 0.3 mg/mL in a 1:2 solution of DMF:PBS (pH 7.2), approximately 2 mg/mL in DMSO, and approximately 5 mg/mL in DMF. The product is not classified as a hazardous substance or mixture according to the Globally Harmonized System (GHS) and is described as stable under normal conditions, though it is incompatible with strong acids, strong bases, and strong oxidizing agents. Recommended storage is in tightly closed containers kept in a dry, cool, and well-ventilated place. Supplier contact for emergencies is 1-800-667-0322.