IWP-2, 1 mg

A laboratory chemical supplied by STEMCELL Technologies, this compound is the WNT pathway inhibitor known as IWP-2 (Inhibitor of WNT Production-2). It acts at the level of the pathway activator Porcupine.

According to the manufacturer's Safety Data Sheet, the substance is a crystalline solid with molecular formula C22H18N4O2S3 and molecular weight 466.6 (CAS 686770-61-6). Reported solubilities include approximately 0.3 mg/mL in a 1:2 solution of DMF:PBS (pH 7.2), ~2 mg/mL in DMSO, and ~5 mg/mL in DMF. The product is stable under normal conditions and is not classified as a hazardous substance or mixture according to the Globally Harmonized System (GHS) or the 2012 OSHA Hazard Communication Standard (29 CFR 1910.1200).

It is intended for laboratory research use only and not for human or animal diagnostic or therapeutic applications unless otherwise stated. Recommended storage is in tightly closed containers kept in a dry, cool and well-ventilated place; incompatible materials include strong acids, strong bases, and strong oxidizing agents.