Cyclopamine, 1 mg

From STEMCELL Technologies' small molecules portfolio, this compound is identified as a Hedgehog pathway inhibitor acting on Smoothened and is listed for differentiation research. Synonyms recorded on the Safety Data Sheet include 11-Deoxojervine and Jervine.

The Safety Data Sheet describes the substance as a crystalline solid at 100% concentration, with the molecular formula C27H41NO2 and a molecular weight of 411.60. The compound is reported as chemically stable, with strong oxidizing agents listed as incompatible materials. Reported solubility values are approximately 0.25 mg/mL in 1:3 EtOH:PBS (pH 7.2), approximately 10 mg/mL in EtOH, and approximately 2 mg/mL in DMF.

The product is not classified as a hazardous substance or mixture and is not classed as dangerous goods under DOT, ADR/RID, IMDG or IATA transport regulations. It is supplied for research use only and is not intended for human or animal diagnostic or therapeutic uses. Recommended handling includes avoiding breathing dust, fumes, gas, mist, vapours or spray and avoiding prolonged or repeated exposure. Storage guidance is to keep the container tightly closed and to follow the product insert.