CHIR99021, 10 mg

A small-molecule research compound supplied by STEMCELL Technologies, this product is identified as CHIR99021 and is documented for use as a Wnt pathway activator and GSK3 inhibitor. It is presented as a crystalline solid with a molecular formula of C22H18Cl2N8 and a molecular weight of 465.30. The substance is assigned CAS No. 252917-06-9 and is described by synonyms including CT 99021. Solubility information from the manufacturer states approximately 50 mg/mL in DMSO, with other source data indicating ~2.5 mg/mL in DMSO and ~1.4 mg/mL in PBS (pH 7.2).

The compound is classified as a laboratory chemical and carries GHS hazard classifications including acute oral toxicity, skin corrosion/irritation, and serious eye damage/eye irritation. The safety documentation lists hazard statements such as harmful if swallowed, causes skin irritation, causes serious eye damage, and suspected of damaging fertility or the unborn child. Recommended handling includes wearing protective gloves, eye and face protection, working in a well-ventilated area, and avoiding breathing dust or vapours. In case of exposure, first-aid guidance directs users to rinse skin or eyes with water for at least 15-20 minutes, remove to fresh air if breathing is impacted, and seek immediate medical attention.

Storage recommendations advise keeping the container tightly closed and storing in accordance with the product information sheet, out of the reach of children. The product is supplied by STEMCELL Technologies, with the supplier identified as STEMCELL Technologies Canada Inc., Vancouver, Canada, and STEMCELL Technologies SARL, Grenoble, France.