Camostat (Mesylate), 10 mg

Provided by STEMCELL Technologies, this small molecule is a serine protease inhibitor with antiviral properties. It inhibits the transmembrane serine protease TMPRSS2, which is involved in viral infections such as COVID-19. The compound is supplied as the mesylate salt and is also known by the alternative names Foipan and FOY 305. Its chemical formula is C20H22N4O5 • CH3SO3H, with a molecular weight of 494.5 g/mol and a stated purity of ≥ 98%. It presents as a crystalline solid.

According to the product information, the compound is stable at -20°C as supplied; prolonged exposure to light should be avoided, and a desiccant is recommended for long-term storage. It remains stable as supplied for 12 months from the date of receipt. The stated solubility in DMSO is ≤ 50 mM, and the compound has low solubility in aqueous media. Published applications include inhibition of MCP-1 and TNF-alpha production in monocytes, and inhibition of the proliferation and activation of pancreatic stellate cells in rats. The accompanying safety data sheet notes that the chemical causes skin irritation and serious eye irritation, may cause respiratory irritation, and is very toxic to aquatic life with long lasting effects. Products are for research use only and are not intended for human or animal diagnostic or therapeutic uses.