AM580, 10 mg

STEMCELL Technologies offers this research-grade retinoid compound as a selective agonist of retinoic acid receptor (RAR) alpha, supporting studies in reprogramming, mesodermal differentiation, and cancer cell growth. The product is positioned within research workflows for defined, xeno-free induction of early mesodermal differentiation and for non-integrating, self-replicating RNA reprogramming to generate iPS cells.

Also known by the synonyms CD336, NSC 608001, and Ro 40-6055, the substance is 4-[[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbonyl]amino]-benzoic acid (CAS No. 102121-60-8) with molecular formula C22H25NO3 and a molecular weight of 351.4. It is supplied as a crystalline solid. Reported solubilities are approximately 0.5 mg/mL in a 1:1 solution of DMF:PBS (pH 7.2), approximately 10 mg/mL in EtOH, approximately 20 mg/mL in DMSO, and approximately 25 mg/mL in DMF.

The compound is not classified as a hazardous substance or mixture according to the Globally Harmonized System (GHS) or the 2012 OSHA Hazard Communication Standard and is described as stable under normal conditions. It is intended for laboratory research use, with storage conditions detailed on the Product Information Sheet. Incompatible materials include strong oxidizing agents.