AGK2, 1 mg

This laboratory chemical from STEMCELL Technologies is a small-molecule SIRT2 inhibitor. The substance is identified as (E)-2-cyano-3-[5-(2,5-dichlorophenyl)furan-2-yl]-N-quinolin-5-ylprop-2-enamide, with molecular formula C23H13Cl2N3O2 and molecular weight 434.3. It is supplied as a crystalline solid at 100% concentration (CAS 304896-28-4). Reported solubility values are approximately 0.3 mg/mL in 1:2 DMF:PBS (pH 7.2), approximately 1 mg/mL in DMSO, and approximately 3 mg/mL in DMF.

The compound is classified for Eye Damage/Irritation, Category 2A, with the signal word Warning and hazard statement H319: Causes serious eye irritation. It is chemically stable and should be kept away from strong oxidizing agents, strong reducing agents, strong acids, and strong bases. Hazardous decomposition products include carbon dioxide, carbon monoxide, hydrogen chloride gas, and nitrogen oxides.

For safe handling, use compatible chemical-resistant gloves, a lab coat, safety glasses, and a NIOSH (US) or CEN (EU) approved respirator as conditions warrant. Avoid breathing dust, fume, gas, mist, vapours, or spray, and avoid prolonged or repeated exposure. Keep the container tightly closed and store in accordance with the product insert. In case of eye contact, rinse cautiously with water for several minutes and seek medical advice if irritation persists.