3-Methyladenine, 100mg

A selective class III PI3K inhibitor widely deployed in mammalian cell culture research, 3-Methyladenine (3-MA) blocks autophagosome formation and is used by laboratories studying macroautophagy, apoptosis, and mitophagy. Supplied by STEMCELL Technologies as 100 mg of solid reagent, this small molecule is prepared as a stock solution in DMSO or sterile water and applied directly to culture media; working concentrations are commonly prepared around 5 mM for in vitro assays. The compound is routinely paired with late-stage autophagy inhibitors such as chloroquine or bafilomycin A1 to distinguish initiation from lysosomal blockade, and is used across cancer biology, neurodegeneration, immunology, and cell-signaling workflows. The vial should be stored at room temperature, protected from moisture and light, and is intended for research use only.