3-Deazaneplanocin A , 1 mg

An epigenetic modifier from STEMCELL Technologies, this small molecule is designed to inhibit EZH2 lysine methyltransferase. The compound, 3-Deazaneplanocin A, is identified chemically as (1S,2R,5R)-5-(4-aminoimidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol and is also referenced under the synonyms DZNep and NSC 617989. It carries CAS registry number 102052-95-9, with molecular formula C12H14N4O3 and molecular weight 262.30.

The product is supplied as a crystalline solid. Reported solubility values are approximately 10 mg/mL in PBS (pH 7.2), approximately 1 mg/mL in EtOH, and approximately 20 mg/mL in DMF and DMSO. The substance is described as chemically stable, with strong oxidizing agents listed as incompatible materials.

Per the manufacturer's Safety Data Sheet, the compound carries GHS hazard categories including Acute Toxicity, Oral (Category 4); Skin Corrosion/Irritation (Category 2); Serious Eye Damage/Eye Irritation (Category 2); and Target Organ Systemic Toxicity (single exposure, Category 3). Listed hazard statements include "harmful if swallowed" (H302), "causes skin irritation" (H315), "causes serious eye irritation" (H319), and "may cause respiratory irritation" (H335). The supplier is identified as STEMCELL Technologies SARL, based in Grenoble, France.