EZ1 Advanced XL, PrioPLUS

An automated workstation for nucleic acid purification, this QIAGEN benchtop instrument processes up to 14 samples per run using prefilled, sealed reagent cartridges that minimize manual handling and cross-contamination risk. Magnetic-bead particle technology isolates DNA, viral RNA, and bacterial DNA from serum, plasma, swabs, urine, and tissue lysates in roughly 30 to 45 minutes per batch.

A 200 µL sample volume is loaded into a disposable sample tube paired with the appropriate EZ1 reagent cartridge. The robotic head then binds nucleic acids to silica-coated magnetic beads, performs a series of wash steps to remove inhibitors, and elutes purified nucleic acid ready for downstream PCR, RT-PCR, sequencing, or other amplification reactions. Typical yields range from 1 to 10 µg per sample depending on starting material and protocol.

The color touchscreen interface runs pre-loaded protocols with minimal training, allowing bench staff to load samples, select a kit, and walk away. Built-in UV decontamination and an internal HEPA filtration stage protect sample integrity during infectious disease workflows, while barcode reading of reagent cartridges supports full traceability of consumables and batch records.

The PrioPLUS configuration extends the standard platform with an extended service agreement, priority technical contact, and qualification documentation suitable for regulated laboratories operating under 21 CFR Part 11 environments. It is commonly deployed in clinical microbiology labs performing viral load testing, respiratory pathogen panels, STI screening, and genotyping assays where standardization, traceability, and rapid turnaround time matter.