Tauroursodeoxycholic Acid (Na salt), 1 g

A hydrophilic bile acid conjugate widely used in cell biology and biochemical research, tauroursodeoxycholic acid sodium salt (TUDCA) acts as a chemical chaperone that mitigates endoplasmic reticulum stress. The sodium salt formulation is supplied by STEMCELL Technologies as a 1 g powder, intended for stock solution preparation in cell culture media or aqueous buffers. Working concentrations commonly range from 0.5 to 5 mM for in vitro assays examining unfolded protein response signaling, apoptosis pathways, and mitochondrial function.

The compound supports research applications including western blot analysis of ER stress markers such as BiP and CHOP, flow cytometry-based viability studies, and investigations of insulin signaling in metabolic disease models. Store the dry powder at room temperature, protected from light and moisture, with desiccation recommended for long-term stability. Reconstituted stocks are routinely aliquoted and stored frozen to limit freeze-thaw cycles, supporting reproducible dosing across experiments.

This reagent is intended for research use only and is not approved for diagnostic or therapeutic applications. Researchers studying neurodegeneration, hepatic injury, or protein misfolding disorders frequently incorporate this bile acid derivative into cell culture protocols to probe protective mechanisms against cytotoxic insults. STEMCELL Technologies provides the material in a single-use vial format for laboratory workflows requiring defined, lot-controlled chemistry.