Rt Recom TNF-alpha, 10 µg

TNF-alpha is a cytokine that stimulates expression of E- and P-selectins, facilitating cell adhesion to activated platelets and endothelial cells. Biological activity was tested by the ability to inhibit cell growth of mouse L929 cells, with cell viability measured using a fluorometric assay method. The EC50, defined as the effective concentration of the growth factor at which cell proliferation is at 50% of maximum, was determined to be less than 0.05 ng/mL.

The protein was characterized by SDS-PAGE under reducing and non-reducing conditions, followed by visualization with Coomassie Blue staining. The product is supplied as a solid and is not classified as a hazardous substance or mixture according to the Globally Harmonized System (GHS). It is not regulated for transport.

STEMCELL Technologies Canada Inc., based in Vancouver, British Columbia, Canada, supplies this product as a laboratory reagent.