Rt Recom M-CSF, 25 µg

Manufactured by STEMCELL Technologies, this laboratory reagent is a recombinant form of rat macrophage colony-stimulating factor (M-CSF). According to the manufacturer, M-CSF is required for the maturation and activation of monocytes and macrophages and regulates inflammatory responses in conjunction with other stimuli.

The biological activity of the recombinant protein was tested by its ability to promote the proliferation of M-NFS-60 cells, with cell proliferation measured using a fluorometric assay method. The EC50, defined as the effective concentration of the growth factor at which cell proliferation is at 50% of maximum, is less than 2.5 ng/mL. The product has also been characterized by resolving 2 μg of Rat Recombinant M-CSF with SDS-PAGE under reducing and non-reducing conditions, followed by visualization with Coomassie Blue staining.

The safety data sheet indicates that the material is supplied as a solid and is not classified as a hazardous substance or mixture according to the Globally Harmonized System (GHS). Storage conditions are described in the accompanying Product Information Sheet, and the manufacturer's recommended emergency telephone is provided for incident response.