(R)-(+)-BAY-K8644, 10 mg

A laboratory reagent supplied by STEMCELL Technologies, (+)-Bay K8644 is described as a modulator of calcium channels that exists as two enantiomers with opposite actions. The substance is also referenced by the synonyms (+)-Bay-K 8644, (+)-Bay-R 4407, (R)-(+)-Bay K 8644, NI 105, and R 4407.

The chemical identity is R-(+)-1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid methyl ester (CAS 98791-67-4), with a molecular formula of C16H15F3N2O4 and a molecular weight of 356.3. It is supplied as a solid with a crystalline appearance. Reported solubility values are DMF at 50 mg/mL, DMSO at 50 mg/mL, Ethanol at 50 mg/mL, and Ethanol:PBS (pH 7.2) (1:9) at 0.1 mg/mL.

The product carries a Warning label and is classified as Skin corrosion/irritation Category 2 and Serious eye damage/eye irritation Category 2A, with hazard statements indicating it causes skin irritation and serious eye irritation. The safety data sheet notes that 100 % of the mixture consists of ingredient(s) of unknown toxicity. The compound is incompatible with strong oxidizing agents and is stable under recommended transport or storage conditions; hazardous decomposition products include carbon dioxide, carbon monoxide, hydrogen fluoride, and nitrogen oxides.