QIAseq Multimodal Index I Sets AB (96)

A component of the QIAGEN QIAseq Multimodal HT Panels system, this index set supports consolidated targeted DNA and RNA enrichment and analyses. The system prepares UDI-containing, Illumina-compatible targeted DNA and RNA libraries from total nucleic acids (or DNA + RNA) using a single-day, consolidated workflow, conserving samples of limited availability and avoiding the need for two separate workflows for DNA and RNA analysis.

The workflow is designed for use with low-yield and poor-quality biological samples. The library insert size is approximately 150 bp, making the system highly compatible with low-quality samples such as FFPE samples. The ability to simultaneously detect DNA and RNA biomarkers from total nucleic acids has been benchmarked against two separate workflows, namely QIAseq Targeted DNA Pro and QIAseq Targeted Fusion XP.

Detectable DNA biomarkers include single nucleotide variants (SNVs), insertions and deletions (InDels), and copy number variants (CNVs). Detectable RNA biomarkers include fusions, exon skipping events, and gene expression levels.