Puromycin, 50 mg

From STEMCELL Technologies, this puromycin (dihydrochloride) laboratory chemical is an antibiotic used to select for transgenic cells carrying the Puro-resistance gene. It is suitable for selecting transfected mammalian cells, for selecting transfected prokaryotic and eukaryotic cells, and for use in Tet-inducible gene expression systems.

The substance is a pure solid with a crystalline appearance, a molecular weight of 544.4 and molecular formula C22H29N7O5 • 2HCl. Reported solubility values are approximately 10 mg/mL in PBS (pH 7.2), approximately 1 mg/mL in EtOH, approximately 13 mg/mL in DMSO and approximately 14 mg/mL in DMF. Under Regulation (EC) No 1272/2008 the material is classified as Acute toxicity – Oral Category 4 (H302), Harmful if swallowed.

Recommended use is as a laboratory chemical. Storage should follow the instructions on the Product Information Sheet and the product should be kept out of the reach of children. It is stable under recommended transport or storage conditions, is incompatible with strong oxidizing agents, and on decomposition can yield carbon oxides, hydrogen chloride gas and nitrogen oxides (NOx).