Purmorphamine, 10 mg

The compound 9-cyclohexyl-N-[4-(morpholinyl)phenyl]-2-(1-naphthalenyloxy)-9H-purin-6-amine, supplied by STEMCELL Technologies, is a research reagent used as a Hedgehog pathway activator that directly binds to and activates the Hedgehog receptor Smoothened (SMO). The manufacturer highlights its use in defined, serum-free workflows for neural induction of human ES and iPS cells.

The substance is a crystalline solid with a molecular weight of 520.6 and a molecular formula of C31H32N6O2 (CAS No. 483367-10-8). Reported solubility values are in DMF (20 mg/mL), in DMF:PBS (pH 7.2) at a 1:2 ratio (0.25 mg/mL), and in DMSO (10 mg/mL). According to the manufacturer's Safety Data Sheet, the compound is not classified as hazardous under the 2012 OSHA Hazard Communication Standard (29 CFR 1910.1200) or the Globally Harmonized System (GHS), with 100% of the mixture consisting of ingredient(s) of unknown toxicity. It is recommended for use as a laboratory chemical, and strong oxidizing agents are listed as incompatible materials. Storage should follow the conditions listed on the Product Information Sheet.