Ms Recom MIP-1 alpha (CCL3), 100 µg

STEMCELL Technologies recombinant mouse MIP-1 alpha (CCL3) is a bioactive chemokine supplied as a 100 µg lyophilized powder for immunology and inflammation research. Expressed in Escherichia coli and purified to high homogeneity, the protein signals through CCR1 and CCR5 receptors on monocytes, T lymphocytes, neutrophils, and dendritic cells, making it a useful reagent for chemotaxis assays, transwell migration studies, and receptor-binding experiments in murine systems.

The lyophilized format reconstitutes readily in sterile distilled water or a compatible aqueous buffer. STEMCELL Technologies recommends aliquoting the reconstituted stock to limit freeze-thaw cycles and preserve bioactivity. Unopened vials remain stable when stored refrigerated for short-term use; for long-term storage keep at -20°C or colder. Once reconstituted, protect the solution from light and avoid repeated freeze-thaw cycles. Working concentrations typically fall in the low ng/mL range depending on cell type and assay readout.

Researchers commonly pair recombinant CCL3 with co-culture systems, dendritic-cell differentiation protocols, and Th1-polarization workflows, using downstream readouts such as flow cytometry to characterize leukocyte recruitment and activation. The reagent is intended for research use only and is not approved for diagnostic or therapeutic applications.