Ms Recom IL-19, 50 µg

A laboratory reagent from STEMCELL Technologies, this recombinant mouse interleukin-19 (IL-19) is supplied for research applications. According to the manufacturer's product information, IL-19 induces T-helper cell differentiation and is considered a proinflammatory cytokine.

Biological activity has been evaluated by its ability to promote the proliferation of MCF-7 cells, measured using a fluorometric assay method. The EC50 is defined as the effective concentration of the cytokine at which cell proliferation is at 50% of maximum, and in the cited example is less than 50 ng/mL. SDS-PAGE analysis under reducing and non-reducing conditions, with Coomassie Blue staining, indicates a predicted molecular mass of 17.7 kDa.

The safety data sheet describes the material as a solid that is not classified as a hazardous substance or mixture according to the Globally Harmonized System (GHS). It is stable under recommended transport and storage conditions and is not regulated for transport by DOT, TDG, MEX, ICAO, IATA, IMDG, RID, ADR, or ADN. The supplier is STEMCELL Technologies Canada Inc., based in Vancouver, British Columbia.