Ms Recom G-CSF, 1000 µg

A recombinant cytokine from STEMCELL Technologies, Mouse Recombinant G-CSF stimulates the initial proliferation of granulocyte-macrophage progenitors and supports the survival of erythroid and eosinophil progenitors. Biological activity was assessed by promoting the proliferation of NFS-60 cells, with cell proliferation measured after 69 hours of culture using a fluorometric assay method. The EC50 is defined as the effective concentration of the growth factor at which cell proliferation is at 50% of maximum, and in the cited example the EC50 is 8 - 12 pg/mL. The protein has a predicted molecular mass of 19.1 kDa; 2 μg of the product resolved with SDS-PAGE under reducing (+) and non-reducing (−) conditions and visualized by Coomassie Blue staining.

According to the manufacturer's Safety Data Sheet, the product is a laboratory reagent supplied as a solid powder and is not classified as a hazardous substance or mixture according to the Globally Harmonized System (GHS). It is stable under normal conditions, with no possibility of hazardous reactions under normal processing. Recommended storage is to keep containers tightly closed in a dry, cool, and well-ventilated place, and to handle the product in accordance with good industrial hygiene and safety practice. The product is not regulated for transport by DOT, TDG, MEX, ICAO, IATA, IMDG, RID, or ADR. It is intended for research use only and is not intended for human or animal diagnostic or therapeutic uses unless otherwise stated, and STEMCELL Technologies' quality management system is certified to ISO 13485.

The environmental impact of this product has not been fully investigated, and no data are available on persistence and degradability, bioaccumulation, or other adverse effects.