miRCURY LNA Custom Inhibitor invivoLS(A) - Large Scale Invivo 100mg

Custom-designed antisense reagents from QIAGEN silence specific microRNAs in living organisms using Locked Nucleic Acid chemistry. This miRCURY LNA inhibitor is produced at large scale and purified for in vivo delivery, supporting preclinical studies that require sustained knockdown of a target miRNA across multiple animals or repeated dosing schedules. The 100 mg bulk format accommodates extensive dose-response, time-course, and multi-group experiments without repeated reordering. Each oligonucleotide is synthesized to the user-defined sequence, quality-checked by mass spectrometry, and shipped with a certificate of analysis confirming identity, purity, and yield. The material is supplied as a dried pellet; reconstitute in nuclease-free water or PBS to a convenient stock (commonly 1 to 10 mg/mL) and dilute into the appropriate delivery vehicle before administration. Store dry at -20 °C, protect from light, and once reconstituted aliquot to limit freeze-thaw cycles, keeping working stocks refrigerated or frozen depending on the dosing schedule. Compatible with standard in vivo routes including intravenous, intraperitoneal, subcutaneous, and local tissue administration in rodent and larger animal models, the reagent is intended for research use only and integrates with downstream readouts like RT-qPCR, northern blot, and RNA sequencing to confirm target engagement.