Microarray Service

End-to-end gene expression and genotyping analysis delivered through QIAGEN's Sample to Insight workflow streamlines large-scale transcriptomic studies for research laboratories. Researchers submit RNA, DNA, or tissue samples which are processed using industry-standard array platforms, with integrated quality control checkpoints ensuring data integrity at every step. The service includes nucleic acid extraction when needed, sample QC via Bioanalyzer or spectrophotometry, hybridization to microarray chips, scanning, and primary data analysis. Output deliverables include raw CEL files, normalized expression data, and detailed QC reports supporting downstream bioinformatics work.

Sample submission requirements typically include a minimum of 50 ng total RNA with an RIN value above 7, or 200 ng genomic DNA, shipped in nuclease-free tubes on dry ice to maintain cold-chain integrity. Upon receipt, samples should be stored at -80°C and protected from light until processing to prevent degradation. Researchers receive processed data files plus a written interpretation report identifying differentially expressed genes, enriched pathways, and quality metrics within a turnaround measured in weeks depending on project scope.

Applications span differential gene expression analysis across treatment conditions, SNP genotyping for population studies, copy number variation detection in tumor versus normal pairs, and biomarker discovery in clinical research samples. The microarray workflow complements next-generation sequencing by providing a cost-effective alternative for hypothesis-driven studies where whole-transcriptome sequencing would be excessive. Both single-sample submissions and large cohort studies are supported through this contract research offering.