Metformin, 5 g

A widely cited biguanide reference compound, metformin hydrochloride is supplied as a 5 gram crystalline powder unit by STEMCELL Technologies for metabolic research and disease modeling. The reagent supports in vitro studies of glucose homeostasis, AMPK signaling, insulin response, and mitochondrial function across hepatocyte, myocyte, and pancreatic beta-cell cultures.

Working concentrations typically span 0.1 to 10 mM in cell culture media, with dose-response assays used to characterize antiproliferative, anti-inflammatory, and cytoprotective effects in cancer metabolism, polycystic kidney disease, and cellular aging programs. Investigators also rely on this small molecule to probe the mTOR pathway, examine mitochondrial respiration via Seahorse-style readouts, and screen combination treatments in diabetes and oncology workflows.

Store at room temperature in the original sealed bottle, protected from light and moisture; the reagent retains activity for a multi-year shelf life when handled under dry conditions. Stock solutions are commonly prepared at 100 mM in sterile water, refrigerated for short-term use, and aliquoted to minimize freeze-thaw cycles during extended studies.

Packaged in a single use bottle format, the product is intended for research use only and is compatible with standard pharmacological, biochemical, and cell biology assay pipelines in academic and biopharmaceutical laboratories.