Metformin, 1 g

For cell biology and metabolic research, this biguanide compound is supplied as a 1 g unit of research-grade metformin for laboratory studies of energy sensing and signaling pathways. The molecule functions as an activator of AMP-activated protein kinase (AMPK) and as an indirect inhibitor of the mTOR pathway, making it a standard pharmacological probe in investigations of cellular energy homeostasis, insulin signaling, glucose uptake, and autophagy flux. In stem cell workflows, the agent is frequently used to modulate mitochondrial respiration, support differentiation protocols, and maintain cultures of intestinal organoids, hepatocytes, and other metabolically active cell types. Researchers also apply it in cancer cell line panels, senescence and aging models, and diabetes pathogenesis assays. The compound is provided as a stable solid powder that stores at room temperature in a tightly sealed container, protected from moisture and light, and is intended for research use only, not for diagnostic or therapeutic applications. STEMCELL Technologies supplies the reagent in a single-use vial format, allowing laboratories to prepare fresh working stock solutions in sterile water or buffer for each experiment.