(-)-Indolactam V, 1 mg

Supplied by STEMCELL Technologies, this indole alkaloid compound is documented to activate protein kinase C (PKC). It interacts with multiple PKC isozymes, binding to the α, β, γ, δ, ε, and η isozymes with reported Ki values of 11, 6, 19, 8, 22, and 16 nM, respectively.

The molecule has a molecular weight of 301.4 g/mol and a chemical formula of C17H23N3O2. It is described as a white to off-white solid with a stated purity of ≥95%. The accompanying safety data sheet classifies it as not a hazardous substance or mixture according to the Globally Harmonized System (GHS). Reported solubility includes DMSO at ≤30 mM and absolute ethanol at ≤15 mM.

In published research, the compound has been used to promote differentiation of human and mouse pluripotent stem cell-derived definitive endoderm toward pancreatic precursors, supporting workflows in directed pancreatic lineage development.