Hu Recom TPO, 100 µg

According to STEMCELL Technologies, TPO functions as a key regulator of megakaryocytopoiesis and thrombopoiesis in vitro and in vivo. Their Human Recombinant TPO is a recombinant protein supplied as a solid (powder) and is recommended for use as a laboratory reagent.

The biological activity of the product has been tested by its ability to promote the proliferation of MO7e cells, with cell proliferation measured using a fluorometric assay. The EC50 is defined as the effective concentration of the growth factor at which cell proliferation is at 50% of maximum. In the reported example, the EC50 is 10.2 ng/mL. Indicated research workflows include serum-free culture supplementation for expansion of human CD34+ hematopoietic cells, expansion and differentiation of human granulocytes, expansion of human megakaryocytes, and expansion of human hematopoietic cells.

Per the safety data sheet, the product is not classified as a hazardous substance or mixture under the 2012 OSHA Hazard Communication Standard (29 CFR 1910.1200) or the Globally Harmonized System (GHS), and it is not regulated for transport by DOT, TDG, MEX, ICAO, IATA, IMDG, RID, ADR, or ADN. The manufacturer's quality management system is certified to ISO 13485, and the product is for research use only.