Hu Recom Oncostatin M, 10 µg

A human recombinant signaling protein supplied by STEMCELL Technologies as a cytokine for immunology and stem cell research. Cytokines are small, secreted proteins that affect signaling in a variety of cell types. This preparation plays a role in cell proliferation, hematopoiesis, inflammation, liver development, and bone formation and resorption, and is grouped with related factors including a glucocorticoid pathway activator, granulocyte colony-stimulating factor, interleukin 6, and leukemia inhibitory factor.

Biological activity is verified by the protein's ability to promote proliferation of TF-1 cells, with cell proliferation measured using a fluorometric assay method. The EC50, defined as the effective concentration of the growth factor at which proliferation is at 50% of maximum, is less than 10 ng/mL. The protein has a predicted molecular mass of 25.9 kDa, and 2 μg resolved by SDS-PAGE under reducing (+) and non-reducing (-) conditions can be visualized by Coomassie Blue staining. Like other recombinant cytokines from this supplier, the product carries a guaranteed purity of ≥ 95% and endotoxin levels of ≤ 0.2 EU/μg protein to support consistency and reproducibility across multiple applications.

Supplied as a solid laboratory reagent, the material is not classified as a hazardous substance or mixture according to the Globally Harmonized System (GHS) and is intended for research use only.